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ANN ARBOR, Mich. -- The text message hit Michigan?cornerback Jourdan Lewis cell phone sometime after midnight on Nov. 13, only a couple of hours after Iowa upset the Wolverines 14-13 in Iowa City, a loss that put a serious dent in the their Big Ten title and College Football Playoff hopes.The text message from Lewis friend Tucker Vasher read: Keep your head up. Tough times bring out the best! Shows you how tough you are. No matter what I love you, bro. Go Blue!Lewis, an All-America candidate and potential first-round pick in next springs NFL draft, knows that few people are as tough or inspirational as Tucker and his twin brother, Tyler. The 22-year-old Michigan fans were born with osteogenesis imperfecta, a genetic disorder that is commonly known as brittle bone disease and which requires them to use wheelchairs for their entire lives.It is inspiration that Lewis will carry into Saturdays game at No. 2 Ohio State (noon ET, ABC/ESPN App), which might decide whether the Buckeyes or No. 3 Wolverines remain in the playoff hunt.Just the way they live their lives is amazing, Lewis said. They dont fear anything. When I think of them, I realize that Im not really going through too much, and I can come back from anything. Even with everything theyre dealing with, theyre still enjoying their lives. Theyre optimistic no matter what.Between them, the Vasher twins have broken 75 to 100 bones, according to their mother, Lisa Vasher, of Harrison, Michigan.They were born with broken bones, she said. They had to take the boys out by C-section so they wouldnt break anything else.About 20 weeks into her pregnancy in 1994, doctors told Lisa and her husband Jeff that something was wrong with their unborn twins. When doctors completed an ultrasound, they discovered their babies femurs were irregularly short and curved. Doctors feared the boys suffered from brittle bone disease.They didnt expect the boys to survive, Lisa said.According to statistics from the Osteogenesis Imperfecta Foundation, there are a minimum of 20,000 people and maybe as many as 50,000 living with brittle bone disease in the U.S. Its much rarer for twins to both have the condition. Lisa Vasher said she has met only two other sets of twins who have osteogenesis imperfecta.Despite their struggles, Tucker and Tyler have never allowed their condition to prevent them from doing what other people do. When they were younger, they sometimes attended school wearing full-body casts. A nurse was assigned to keep watch over them at school, and their friends made sure other students didnt bump into their wheelchairs. Their bones are that fragile.Each of the Vasher twins has titanium rods in both their shins and their hips to keep them straight and strong. Tucker also has rods in both forearms and biceps; Tyler has a rod in his left bicep. The titanium, TV antenna-like rods in their shins expand as their bones grow.Tucker and Tyler know they can break a bone at any minute, regardless of the precautions they might take. Tucker broke a rib while sneezing and broke his arm while picking up a small Diet Coke at McDonalds. When they were younger, their parents wouldnt allow them to watch horror movies because they feared the boys would break a bone if they were startled.A couple of years ago, Tucker broke his arm while fishing in the lake behind his familys home in the upper peninsula of Michigan. He was using light tackle, only a bobber and worm, but when he opened the bale and flicked a line into the water, his arm snapped in half.Fishing was the one thing you couldnt take away from me, Tucker said. It was the one thing I was allowed to do. Right there, my fishing career was over. I could never fish again.That summer, Tucker broke his arm four times in three weeks. When doctors repaired his left arm, they rolled him over on the operating table and accidentally broke his right arm. Another time, Tucker fell out of his wheelchair and into an old fire pit. He broke both legs and arms and had to spend a couple of months in bed.There are a lot of cases that are worse than us, Tyler said. There are some kids that have to lay in bed up against a pillow all day. Believe it or not, were pretty fortunate.The Vasher brothers spend a lot of their time on social media and playing video games. Tucker is very active on Twitter -- he has tweeted more than 38,000 times and has more than 4,000 followers. Tyler is a little less active but still has tweeted more than 16,000 times to his more than 1,400 followers. Neither one is shy about sending messages to professional athletes and other famous people.The brothers have had online interactions with Los Angeles Angels star Albert Pujols, Detroit Lions quarterback Matthew Stafford, former Lions running back Barry Sanders and Atlanta Falcons receiver Julio Jones. Angels All-Star outfielder and AL MVP Mike Trout even sent them an autographed bat.A couple of years ago, Detroit Lions defensive lineman Ndamukong Suh invited the Vasher twins to watch a game from his luxury suite. Detroit Tigers All-Star pitcher Justin Verlander gave them on-field passes to a game against the Angels, and they were able to meet Verlander and Trout.Tucker is amazing, Lisa said. Tucker is Mr. Social Media and is all about it. Theyve been through so much. When I see them happy and doing what they love, it makes me happy.Few things make the Vasher twins happier than watching Michigans football team play. Their uncle, Jim Vasher, was a Michigan season-ticket holder and took the brothers to a few games in the past. Jim, a military veteran, wore the same clothes to every game -- khaki pants and a Michigan shirt. He started the routine long before Wolverines coach Jim Harbaugh made the conservative attire famous.About a year ago, Tucker started an online conversation with Lewis, one of his favorite Michigan players.We started talking to each other on Twitter, and I asked him what he liked to do when he wasnt playing football, Tucker said. He said he liked to play video games, and we started playing Xbox.Eventually, Tucker and Tyler started playing online Xbox with Lewis and his teammates, including tailback DeVeon Smith, defensive end Taco Charlton and safety Delano Hill. The Vasher twins forged a friendship with the Michigan players by playing games like Call of Duty, Madden NFL 17 and NBA 2K, while chatting online with them for hours.We just had conversations with them while we were playing the games, Lewis said. They were Michigan fans and seemed like really good guys.After Tucker had surgery at the University of Michigan Health System in Ann Arbor this past spring, Lewis and his girlfriend visited him while he was recovering. Tucker invited Lewis to visit his home in Harrison, which is about 160 miles northwest of Michigans campus.On April 23, Tyler and two of his friends drove to Ann Arbor to pick up Lewis. A native of Detroit, Lewis didnt know what to expect. Harrison has about 2,100 residents and only two stoplights. Theres a seasonal Dairy Queen and not much else. There isnt a lot to do besides hunting and fishing. Harrisons schools are even closed on the opening day of deer season each fall.When Lewis arrived in Harrison, the first thing the Vasher twins asked him to do was dunk a basketball. They had never seen anyone do it in person. Then they spent the rest of the day playing video games and doing other things, like hitting golf balls over the lake with a baseball bat and shooting pellet guns.It was probably one of the best times Ive ever had, Lewis said. Theyre some of the kindest people Ive ever met. They welcomed me into their home and didnt even know me. Theyre just really great people. Im so glad I met them.Sometime Saturday morning, Tucker will send Lewis another text message of encouragement. Its a message Lewis wont take for granted.What I bring from my life to his is to always be appreciative, Tucker said. With all of my tragedies, I try to bring out all the positives. I love my life. I couldnt be more thankful. Anything can happen in one second to where your life is changed. 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Speaking Thursday on TSN 1050 Thursday, the Leafs GM also touched on the questions surrounding the teams leadership and the struggles of his big-name free-agent signing. “Its not from lack of effort from the coaching staff.ZAGREB, Croatia -- Juventus big summer signings proved their worth as Miralem Pjanic and Gonzalo Higuain helped the Italian side to a 4-0 win at Dinamo Zagreb in the Champions League on Tuesday.Pjanic scored one and set up another to put Juventus firmly in charge at halftime. Paulo Dybala and Dani Alves sealed matters after the break.Juventus moved top of Group H, level on points with Sevilla after the Spanish side beat Lyon 1-0. Dinamo, which lost 3-0 at Lyon in the first round of fixtures, remained bottom.After a massive outlay in the offseason on new players, a sixth successive Serie A title seemed a foregone conclusion for Juventus, while great things were also expected in the Champions League from the Turin club, which finished runners-up in 2015.Juventus leads Serie A but it has not all been plain sailing for Massimiliano Allegris team, and it drew 0-0 at home to Sevilla in its opening match in Europes elite club competition.Weve been together for 40 days and were working well, but we need a bit of time because there are new players to fit in, Allegri said.The risk this year is that we break with tradition: there could be the illusion that, having signed great players, we can easily win all the matches. Instead, we have to keep our usual attitude. Keeping our feet on the ground is the most important thing, not losing sight of our aims and working hard.Juventus is already without several key players because of long-term injuries and there were fears another would be added to the list when Pjanic, who had to receive treatment following an early challenge, was substituted at halftime.But the Bosnia and Herzegovina midfielder, who signed for 32 million euros ($36 million) from Roma in the offseason, is confident of recovering in time for the weekend.Today we were better at finding spaces, we followed Allegris instructions and you ssaw the results, Pjanic said.ddddddddddddI took a knock on the calf, but I hope to recover as soon as possible and be on the pitch at Empoli.Juventus dominated from the start and broke the deadlock in the 24th minute after Dinamo defenders Gordon Schildenfeld and Leonardo Sigali got in each others way. Sigali attempted to head Leonardo Bonuccis ball back to his goalkeeper, Pjanic nipped in behind and slotted the ball into the bottom right corner.Schildenfeld almost immediately atoned for his error with Dinamos best chance of the match but headed Domagoj Antolics free kick onto the crossbar with Gianluigi Buffon beaten.Pjanic helped Juventus double its lead in the 31st with a stunning pass for Higuain to chest down and volley into the bottom far corner.Higuain transferred from rival Napoli for 90 million euros ($99 million) after scoring 36 goals last campaign to break a 66-year-old Serie A record.Dinamo was offering little resistance and Dybala extended Juves lead with a stunning strike, sending the ball swerving into the top near corner from more than 30 yards (meters).Dani Alves, who was also signed in the offseason, had done little of note all match but he got on the scoresheet five minutes from time with a deflected free kick.Dinamo goalkeeper Adrian Semper was wrongfooted by the deflection and although the 18-year-old managed to get a hand to the ball, he couldnt keep it out.The only moment for Dinamo fans to cheer was when former player Marko Pjaca, who scored 12 goals for the Croatian side last season, came on as a substitute in the 68th minute for Juventus.Pjaca, who is yet to score for Juventus, also helped Dinamo reach the group stage with two goals in a preliminary round match against FK Vardar. 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